In vitro studies of detoxification by intravenous fat emulsions: mechanism of action and preclinical assessment tools

Authors
D. Krastev, V. Atanasov, Z. Vinarov, S. Tcholakova, N. Denkov
Journal
Clinical Toxicology
Year
2026
Volume
64 (10)
Pages
943-954
D. Krastev, V. Atanasov, Z. Vinarov, S. Tcholakova, N. Denkov
Clinical Toxicology 2026
, 
64 (10)
, 
943-954
Abstract

Introduction: The use of intravenous fat emulsions for treatment of drug intoxication still follows
a trial-and-error approach, due to insufficient understanding of the mechanisms of the process
and lack of predictive in vitro tools.