Cholesterol solubilization: Interplay between phytosterols, saponins and lipid digestion products

Authors
S. Tsibranska-Gyoreva, V. Petkov, V. Katev, D. Krastev, Z. Vinarov, S. Tcholakova
Journal
Colloids Surf. A
Year
2023
Volume
662
Pages
131052
S. Tsibranska-Gyoreva, V. Petkov, V. Katev, D. Krastev, Z. Vinarov, S. Tcholakova
Colloids Surf. A 2023
662
131052
Abstract

High plasma concentrations of cholesterol are associated with cardio-vascular disease complications and high risk of myocardial infarction. The absorption of dietary cholesterol depends on its bioaccessibility, which is in turn influenced by phytosterols, saponins and lipid digestion products. Therefore, we explored the interplay between phytosterols, Quillaja Dry saponin extract (QD), their combinations and lipid digestion on cholesterol bioaccessibility via an in vitro.