In vitro studies of detoxification by intravenous fat emulsions: mechanism of action and preclinical assessment tools

Authors
D. Krastev, V. Atanasov, Z. Vinarov, S. Tcholakova, N. Denkov
Journal
Clinical Toxicology
Year
2026
Pages
1-12
D. Krastev, V. Atanasov, Z. Vinarov, S. Tcholakova, N. Denkov
Clinical Toxicology 2026
1-12
Abstract

Introduction: The use of intravenous fat emulsions for treatment of drug intoxication still follows
a trial-and-error approach, due to insufficient understanding of the mechanisms of the process
and lack of predictive in vitro tools.